4–Aminobenzenesulfonamides. 6-Membered Heterocyclic by A. N. Paruta, R. Piekos

By A. N. Paruta, R. Piekos

One in all 3 volumes which jointly disguise all mentioned solubility information for an enormous pharmaceutical classification: the sulfonamides. a data of solubility information is beneficial in all pharmaceutical examine. released solubility facts for the identify compounds were compiled and significantly evaluated, leading to suggested solubility values which training scientists may well use with self belief. every one quantity contains structural formulae and molecular weight information for the compounds coated, with ease grouped jointly

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Extra info for 4–Aminobenzenesulfonamides. 6-Membered Heterocyclic Substituents and Miscellaneous Systems

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Kimmig, J. 176, 722; Arch. Erg. Dermatol. Hyg. 1938, 1941, 24, 398. 18 COMPONENTS : (1) ORIGINAL MEASUREMENTS: Benzenesulfonamide, 4-amino-N-[4- Gutierrez, [(dimethylamino)sulfonyl]phenyl]-; C1 H 4 1 N 7 30 4S 2; (2) 2-Propanone Anales [515-67-3] (acetone); F. H. Fis. quim. (Madrid) 41, 1945, 537-60. C^H^O; [67-64-1] VARIABLES : PREPARED BY: Temperature EXPERIMENTAL VALUES: t/°C G a E R. 57 10 28 036 21 897 225 129 633 45 8 3 56 4 44 15 29 064 22 519 231 669 654 47 5 3 44 4 31 20 30 092 23 130 238 072 672 49 0 3 32 4 20 25 31 120 23 733 244 354 689 50 9 3 21 4 09 30 31 898 24.

At 37°C Comm available MATERIALS: sulfapyridine supplied. Deionized water was ESTIMATED used. ; Chem, Pharm. Bull. 2417-26. R. ; Kamada, A. [7732-18-5] VARIABLES : One MEASUREMENTS: specified. (authors). was used as 32 COMPONENTS : (1) ORIGINAL Benzenesulfonamide, 4-amino-N-2pyridinyl- (sulfapyridine); C1 H 1 1 N 1 30 2S ; J. [144-83-2] (2) Sodium hydroxide; NaOH; (3) Water; H 20 ; MEASUREMENTS: Rose, F. ; Pharm. Exp. 77, 1943, 127-42. [1310-73-2] [7732-18-5] VARIABLES : PREPARED BY: pH EXPERIMENTAL Therap.

Helv. Chim. Oesterheld, G. Acta 1942, 25, 753. ; 2, 1946, Leya, Expevientia S. 459-60. [50-99-7] [7732-18-5] VARIABLES : PREPARED One temperature: EXPERIMENTAL MEASUREMENTS: BY: 18-19°C R. 2 χ 10~ 4 - 3 mol d m , ( 18-19°C ) is 30 mg% compiler ) . AUXILIARY METHOD/APPARATUS/PROCEDURE : After standing for more than two days the INFORMATION SOURCE AND PURITY OF MATERIALS: Nothing specified. soin of 4-amino-N-4-[(aminosulfonyl)phenyl]benzenesulfonamide was filtered and the sulfonamide was assayed in the filtrate colorimetrically by the method of Druey and Oesterheld (1).

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